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Metabolic & Weight

GLP-1s, fat-loss and metabolic compounds - the most-searched category, home to the FDA-approved blockbusters.

GLP-1 / GIP / glucagon triple agonist

Retatrutide

Investigational once-weekly injectable for obesity/metabolic disease (Eli Lilly, LY3437943).

Investigational

GLP-1 receptor agonist

Semaglutide

FDA-approved weekly injectable / daily oral for diabetes and weight management (Novo Nordisk).

FDA-approved

Dual GIP / GLP-1 agonist

Tirzepatide

FDA-approved weekly injectable for diabetes and obesity (Eli Lilly).

FDA-approved

Long-acting amylin analogue

Cagrilintide

Investigational weekly injectable mimicking the satiety hormone amylin (Novo Nordisk), developed mainly as 'CagriSema' with semaglutide.

Investigational

Modified hGH 176-191 fragment

AOD-9604

Synthetic fragment of growth hormone's fat-metabolism tail, stabilized with an added tyrosine; studied for fat loss.

Research use only

NNMT inhibitor

5-Amino-1MQ

A small quinolinium molecule studied for fat/metabolic research; grouped with peptides commercially but chemically an enzyme inhibitor.

Research use only

hGH C-terminal fragment

HGH Fragment 176-191

The unmodified tail-end fragment of growth hormone studied for fat loss; closely related to AOD-9604.

Research use only

GLP-1 receptor agonist

Dulaglutide

A once-weekly injectable GLP-1 medication used to manage type 2 diabetes and, off-label, to support weight loss.

FDA-approved

GLP-1 receptor agonist

Liraglutide

A once-daily injectable GLP-1 medication approved for both type 2 diabetes and chronic weight management.

FDA-approved

Experimental proapoptotic peptide

Adipotide/FTTP

An experimental peptide designed to destroy the blood vessels that feed fat tissue, causing fat cells to die off.

Research use only

AMPK activator / exercise mimetic

AICAR

A research chemical that switches on the cellular energy sensor AMPK, mimicking some effects of exercise on metabolism.

Research use only

Amino-acid-derived nutrient/supplement

L-carnitine

A naturally occurring nutrient that helps transport fatty acids into cells' mitochondria to be burned for energy.

Supplement / cosmetic

Compounded lipotropic injection

Lipo-C

A compounded injectable blend of fat-metabolism nutrients marketed to support weight loss and energy.

Research use only

Compounded lipotropic + B12 injection

MIC (Lipo-C + B12)

A compounded injection combining methionine, inositol, and choline with vitamin B12, marketed for fat loss and energy.

Research use only

Injectable lipolytic

Lemon Bottle

A South Korean fat-dissolving injectable marketed to break down localized pockets of fat.

Research use only

Vitamin

B12

An essential vitamin given by injection to treat or prevent B12 deficiency and support energy and nerve function.

FDA-approved