Experimental proapoptotic peptide
Adipotide/FTTP
Research use only
Written by pep4U Editorial Team · Last reviewed July 8, 2026
An experimental peptide designed to destroy the blood vessels that feed fat tissue, causing fat cells to die off.
| Class / type | Experimental proapoptotic peptide |
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| Category | Metabolic & Weight |
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| Status (Jul 2026) | Research use only |
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How it works
Targets prohibitin on the vasculature of white adipose tissue and triggers apoptosis of those blood vessels, cutting off the fat's blood supply so fat cells shrink and are reabsorbed.
Known / used for
Investigated in animal models for obesity; showed weight and fat loss in obese monkeys but has not been proven in humans.
Positives
Preclinical studies reported significant fat loss and improved insulin sensitivity in obese rhesus monkeys over about 28 days.
Negatives & risks
An early human trial was terminated over kidney toxicity (nephrotoxicity), and there is no established safe dose or completed human efficacy data.
What people like most (reported community sentiment - not endorsement)
Interest is driven by dramatic animal fat-loss results, but reported human sentiment is minimal given the lack of safe, legal access.
Frequently asked questions
What is Adipotide/FTTP?
An experimental peptide designed to destroy the blood vessels that feed fat tissue, causing fat cells to die off. Targets prohibitin on the vasculature of white adipose tissue and triggers apoptosis of those blood vessels, cutting off the fat's blood supply so fat cells shrink and are reabsorbed.
What is Adipotide/FTTP used or researched for?
Investigated in animal models for obesity; showed weight and fat loss in obese monkeys but has not been proven in humans.
Is Adipotide/FTTP FDA-approved or legal?
NOT FDA-approved: purely experimental with no approved indication, no completed human efficacy trial, and no legal pathway for human use as of 2026.
What are the main risks or downsides of Adipotide/FTTP?
An early human trial was terminated over kidney toxicity (nephrotoxicity), and there is no established safe dose or completed human efficacy data.
Legal / regulatory status
NOT FDA-approved: purely experimental with no approved indication, no completed human efficacy trial, and no legal pathway for human use as of 2026.
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