NNMT inhibitor (small molecule, NOT a peptide)
5-Amino-1MQ
Research use only
Written by pep4U Editorial Team · Last reviewed July 8, 2026
A small quinolinium molecule studied for fat/metabolic research; grouped with peptides commercially but chemically an enzyme inhibitor.
| Class / type | NNMT inhibitor (small molecule, NOT a peptide) |
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| Category | Metabolic & Weight |
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| Status (Jul 2026) | Research use only |
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How it works
Inhibits NNMT, slowing conversion of nicotinamide to 1-methylnicotinamide; may preserve NAD+ salvage and alter adipose energy metabolism.
Known / used for
Preclinical obesity, metabolic dysfunction, NAD+ metabolism research.
Positives
Preclinical effects on fat-cell metabolism and NAD+; reported oral availability and NNMT selectivity.
Negatives & risks
No human trials or established safety; human dosing/effects unknown; gray-market purity unverified.
What people like most (reported community sentiment - not endorsement)
Oral (non-injectable) format; 'novel mechanism' appeal of boosting NAD+ / targeting fat differently from GLP-1s.
Frequently asked questions
What is 5-Amino-1MQ?
A small quinolinium molecule studied for fat/metabolic research; grouped with peptides commercially but chemically an enzyme inhibitor. Inhibits NNMT, slowing conversion of nicotinamide to 1-methylnicotinamide; may preserve NAD+ salvage and alter adipose energy metabolism.
What is 5-Amino-1MQ used or researched for?
Preclinical obesity, metabolic dysfunction, NAD+ metabolism research.
Is 5-Amino-1MQ FDA-approved or legal?
NOT FDA-approved; no approved indication. Sold strictly as a research chemical.
What are the main risks or downsides of 5-Amino-1MQ?
No human trials or established safety; human dosing/effects unknown; gray-market purity unverified.
Legal / regulatory status
NOT FDA-approved; no approved indication. Sold strictly as a research chemical.
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