HomeHormones & Reproductive › HMG

Gonadotropin mixture (menotropins, FSH + LH activity)

HMG

FDA-approved

Written by pep4U Editorial Team · Last reviewed July 8, 2026

A purified hormone preparation containing both follicle-stimulating hormone and luteinizing hormone activity used to stimulate the ovaries or testes.

Class / typeGonadotropin mixture (menotropins, FSH + LH activity)
CategoryHormones & Reproductive
Status (Jul 2026)FDA-approved

How it works

Menotropins deliver combined FSH and LH activity, directly stimulating ovarian follicle growth in women and spermatogenesis in men.

Known / used for

Controlled ovarian stimulation for IVF and other assisted reproduction, ovulation induction in anovulatory women, and stimulating sperm production in hypogonadotropic men.

Positives

Effective at recruiting multiple follicles for IVF; provides both FSH and LH activity in one product; long clinical track record.

Negatives & risks

Ovarian hyperstimulation syndrome, multiple pregnancy, injection-site reactions, abdominal pain/bloating, and need for careful monitoring; expensive.

Frequently asked questions

What is HMG?
A purified hormone preparation containing both follicle-stimulating hormone and luteinizing hormone activity used to stimulate the ovaries or testes. Menotropins deliver combined FSH and LH activity, directly stimulating ovarian follicle growth in women and spermatogenesis in men.
What is HMG used or researched for?
Controlled ovarian stimulation for IVF and other assisted reproduction, ovulation induction in anovulatory women, and stimulating sperm production in hypogonadotropic men.
Is HMG FDA-approved or legal?
FDA-approved as a prescription drug (menotropins, e.g., Menopur) for ovarian stimulation in assisted reproductive technology.
What are the main risks or downsides of HMG?
Ovarian hyperstimulation syndrome, multiple pregnancy, injection-site reactions, abdominal pain/bloating, and need for careful monitoring; expensive.

Legal / regulatory status

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