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GH secretagogue / ghrelin mimetic (hexapeptide)

GHRP-2

Research use only

Written by pep4U Editorial Team · Last reviewed July 8, 2026

A synthetic hexapeptide that potently stimulates the body's own GH release via the ghrelin receptor; more potent than GHRP-6 with less hunger.

Class / typeGH secretagogue / ghrelin mimetic (hexapeptide)
CategoryGrowth Hormone & Muscle
Status (Jul 2026)Research use only

How it works

Agonist at GHS-R1a on pituitary and hypothalamic neurons; strong GH release with comparatively less appetite, cortisol and prolactin than GHRP-6.

Known / used for

No approved use; off-label/research for GH stimulation, body composition, recovery; studied as a GH-secretion diagnostic.

Positives

High peak GH release; less appetite stimulation than GHRP-6; short-acting pulse.

Negatives & risks

Can still raise cortisol/prolactin (dose-dependent); water retention/bloating, fatigue, injection-site reactions; no long-term human data; purity concerns.

Frequently asked questions

What is GHRP-2?
A synthetic hexapeptide that potently stimulates the body's own GH release via the ghrelin receptor; more potent than GHRP-6 with less hunger. Agonist at GHS-R1a on pituitary and hypothalamic neurons; strong GH release with comparatively less appetite, cortisol and prolactin than GHRP-6.
What is GHRP-2 used or researched for?
No approved use; off-label/research for GH stimulation, body composition, recovery; studied as a GH-secretion diagnostic.
Is GHRP-2 FDA-approved or legal?
NOT FDA-approved; research-use-only; not compounding-approved. WADA-banned.
What are the main risks or downsides of GHRP-2?
Can still raise cortisol/prolactin (dose-dependent); water retention/bloating, fatigue, injection-site reactions; no long-term human data; purity concerns.

Legal / regulatory status

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