Angiotensin IV-derived synthetic nootropic peptide
A small orally-stable peptide derived from angiotensin IV that is being researched for its powerful ability to build new brain synapses.
| Class / type | Angiotensin IV-derived synthetic nootropic peptide |
|---|---|
| Category | Cognitive & Nootropic |
| Status (Jul 2026) | Research use only |
It potentiates hepatocyte growth factor (HGF) signaling through the c-Met receptor, enhancing downstream pathways associated in animal models with increased dendritic spine density and synaptogenesis.
Preclinical research into memory, learning, cognitive decline, and neurodegenerative conditions such as Alzheimer's disease.
Reported in rodent studies to be extremely potent at promoting synapse formation and improving memory; orally active and metabolically stable.
No human clinical trials; long-term safety unknown; because it stimulates growth-factor pathways there are theoretical cancer-promotion concerns; sold only as an unregulated research chemical of variable purity.
Biohacker communities report subjective cognitive enhancement, but reports are anecdotal and safety data is absent.
NOT FDA-approved for any indication; it is an unapproved research chemical sold for laboratory use only and is not authorized for human consumption.
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