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Short-acting GHRH analog

CJC-1295 without DAC (Mod GRF 1-29)

Research use only

Written by pep4U Editorial Team · Last reviewed July 8, 2026

The same modified GHRH(1-29) peptide without the albumin-binding DAC, so it clears fast (~30 min) - sold as 'Mod GRF 1-29'.

Class / typeShort-acting GHRH analog
CategoryGrowth Hormone & Muscle
Status (Jul 2026)Research use only

How it works

Binds pituitary GHRH receptors to trigger a short GH pulse mimicking natural release; often paired with a GHRP (e.g., ipamorelin).

Known / used for

No approved use; off-label/research for GH optimization, body composition, sleep, recovery.

Positives

Pulsatile release closer to physiologic patterns; short duration seen as preserving feedback; user-reported recovery/sleep/skin benefits.

Negatives & risks

Requires frequent injections (often 1-3x/day); no long-term human data; possible fluid retention, tingling, injection-site reactions; purity concerns.

Frequently asked questions

What is CJC-1295 without DAC (Mod GRF 1-29)?
The same modified GHRH(1-29) peptide without the albumin-binding DAC, so it clears fast (~30 min) - sold as 'Mod GRF 1-29'. Binds pituitary GHRH receptors to trigger a short GH pulse mimicking natural release; often paired with a GHRP (e.g., ipamorelin).
What is CJC-1295 without DAC (Mod GRF 1-29) used or researched for?
No approved use; off-label/research for GH optimization, body composition, sleep, recovery.
Is CJC-1295 without DAC (Mod GRF 1-29) FDA-approved or legal?
NOT FDA-approved. Same regulatory path as CJC-1295 (Cat 2 2023, removed 2024, pending PCAC). Research-use-only; WADA-banned.
What are the main risks or downsides of CJC-1295 without DAC (Mod GRF 1-29)?
Requires frequent injections (often 1-3x/day); no long-term human data; possible fluid retention, tingling, injection-site reactions; purity concerns.

Legal / regulatory status

NOT FDA-approved. Same regulatory path as CJC-1295 (Cat 2 2023, removed 2024, pending PCAC). Research-use-only; WADA-banned.

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